The Cost of Diagnostic Delay in ATTR CardiomyopathyTransthyretin amyloid cardiomyopathy (ATTR-CM) is progressive and, if left untreated, eventually fatal. Disease-modifying therapy is now available for both wild-type and hereditary disease...3 min read
Test Your Knowledge of ATTR AmyloidosisTransthyretin amyloidosis (ATTR) presents along a spectrum – from a progressive, length-dependent polyneuropathy to an infiltrative cardiomyopathy – and both wild-type and...1 min read
Recognizing ATTR Cardiomyopathy and Its Non-Biopsy DiagnosisTransthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized cause of heart failure, particularly heart failure with preserved ejection fraction (HFpEF), and the arrival of disease-modifying...3 min read
Musculoskeletal Clues That Precede ATTR CardiomyopathyTransthyretin amyloid cardiomyopathy (ATTR-CM) specifically refers to a cardiac diagnosis, but the misfolded transthyretin (TTR) that stiffens the myocardium also deposits in other tissues...3 min read
Monitoring and Staging ATTR CardiomyopathyOnce transthyretin amyloid cardiomyopathy (ATTR-CM) is diagnosed, attention turns to 2 linked questions: how advanced is the disease, and…3 min read
How Patients Adapt to Progressive hATTR PolyneuropathyNeurologists follow disease progression using measures of strength, sensation, gait, and balance. For patients, however, progression is experienced through…2 min read
Hear+Now: An AI-Powered Audio Digest – Inheriting hATTR Polyneuropathy, a Family BurdenTransthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized cause of heart failure, particularly heart failure with...5 min read
Living Undiagnosed With ATTR CardiomyopathyFor the cardiologist or neurologist, transthyretin amyloid cardiomyopathy (ATTR-CM) is defined by objective findings – increased ventricular wall thickness, a restrictive...3 min read
Mechanisms and Selection of Disease-Modifying Therapy in hATTR PolyneuropathyHereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN) is a progressive, multisystem disease in which destabilized transthyretin (TTR) misfolds and deposits...3 min read
